By J. Richard Smith, Giuseppe Del Priore, Robert L. Coleman, John M. Monaghan, John Curtin
(Martin Dunitz) long island Univ., manhattan urban. Atlas for postgraduates focused on the surgical administration of gynecological malignancy. incorporates a complete description of the vast majority of investigative and surgeries required of the gynecological oncologist. supplies transparent written and pictorial guide. contains colour hand-drawn illustrations and photographs.
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Additional resources for An atlas of gynecologic oncology
Karlan BY, Raffel LJ, Crvenkovic G et al (1993) A multidisciplinary approach to the early detection of ovarian carcinoma: rationale, protocol design, and early results, Am J Obstet Gynecol 169:494–501. Kato H, Torigoe T (1977) Radioimmunoassay for tumour antigen of human squamous cell carcinoma, Cancer 40: 1621–8. Kenemans P, van Kamp GJ, Oehr P et al (1993) Heterologous double-determinant immunoradiometric assay CA125 II: reliable second-generation immunoassay for determining CA125 in serum , Clin Chem 39:2509–13.
CA125 level prior to third course of chemotherapy 4. Slope of CA125 exponential regression curve Significant contribution, especially in postmenopausal women Role uncertain Established as an independent prognostic indicator Reflects clinical course in >90% of CA125 positive tumours Detects recurrence with a sensitivity of 84– 94% and a false positive rate of <2% Serial rather then absolute values should be used OVARIAN AND FALLOPIAN TUBE CANCERS 29 Prognostic indicator Screening Differential diagnosis As part of the risk of malignancy index a sensitivity of 71– 85% with a specificity of 96– 97% is achieved (positive predictive value 89%) High-risk population: annual screening with CA125 and ultrasound is widely advocated but is not yet validated Median lead time compared to clinical diagnosis of recurrence is 60–99 days Initial serum levels Postoperative serum levels Monitoring response to treatment Detection of recurrence Criteria used include: 1.
Richter K, Frick H (1985) Die Anatomie des Fascia pelvis visceralis aus didaktischer Sicht, Geburtshilfe Frauenbeilkd 45:275. 3 Tumour markers Usha Menon Ian J Jacobs Since the description of Bence Jones proteins well over a century ago, a variety of substances have been investigated as potential tumour markers. However, the term ‘tumour marker’ remains ill defined. Broadly it can be taken to mean any change that indicates the presence of cancer. In this context, morphological change in exfoliated cervical cells is one of the leading tumour markers in clinical use.
An atlas of gynecologic oncology by J. Richard Smith, Giuseppe Del Priore, Robert L. Coleman, John M. Monaghan, John Curtin